Director, Supply Chain Planning
Department: 110 CMCLocation: Waltham, MA
Company Overview:
Dyne Therapeutics is discovering and advancing innovative life-transforming therapeutics for people living with genetically driven neuromuscular diseases. Leveraging the modularity of its FORCE™ platform, Dyne is developing targeted therapeutics that deliver to muscle and the central nervous system (CNS). Dyne has a broad pipeline for neuromuscular diseases, including clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD) and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. For more information, please visit https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.
Role Summary:
The Director of Supply Chain Planning is responsible for end-to-end inventory and production planning across Dyne’s external supply network. This includes long-range planning (LRP), ensuring uninterrupted clinical supply, and supporting commercial launch readiness through scenario-based planning and risk assessments. This strategic role is critical in executing current planning activities and shaping future supply chain capabilities. The Director collaborates cross-functionally with Process Development, Research, CMC, Quality, Clinical Operations, and Commercial teams. It is an opportunity to help shape the future of Dyne’s supply chain function during a critical period of growth and innovation.
This role is based in Waltham, MA without the possibility of being fully remote.
Primary Responsibilities Include:
- Collaborate with cross-functional partners in CMC, Logistics, Quality, Clinical Operations, and Commercial to develop and maintain a reliable demand and supply plan, ensure uninterrupted product availability for patients, support commercial readiness, and align with the company’s business objectives.
- Maintain an understanding of external manufacturing site capacities, capabilities, and supply risks.
- Identify and implement opportunities to optimize supply chain processes and drive efficiencies.
- Lead scenario planning to evaluate alternative demand and supply assumptions and inform risk mitigation strategies.
- Lead monthly demand and supply planning meetings with cross functional team members as part of our drive to a formal Integrated Business Planning / Sales and Operations Planning process.
- Perform analysis of Dyne portfolio, including inventory projections, supply performance and risks.
- Integrate with other global planning processes to monitor key performance indicators (KPIs) and analyze supply chain data to identify opportunities for improvement and cost savings.
- Author Supply Chain-related standard operating procedures (SOPs) and work instructions.
- Manage relationships with third-party suppliers and vendors to ensure timely delivery of materials and components.
- Ensure compliance with regulatory requirements and quality standards in supply chain operations.
Education and Skills Requirements:
- Bachelor’s degree in Supply Chain, Business, Engineering, or a related field; advanced degree preferred. Minimum of 10 years of relevant experience in a biotech, pharmaceutical, or life sciences environment.
- Ability to effectively plan, prioritize, execute, follow up and anticipate challenges.
- Experience managing complex schedules and priorities in dynamic pharmaceutical, biotech or related environments.
- Ability to work, influence, and gain agreement across multiple functions.
- Strong analytical, problem solving and critical thinking skills.
- Strong knowledge of supply chain best practices, inventory management, and demand forecasting.
- Proficiency in advanced Excel functions and familiarity with planning and analytics tools such as Smartsheet, Visio, ERP systems (e.g., SAP, Oracle), and Power BI.
- Collaborative work style to be part of a team to identify process gaps and develop solutions.
- Excellent interpersonal, verbal, and written communication skills.
- Experience in supply chain, drug development, project management, and/or pharmaceutical manufacturing/packaging.
- In-depth working knowledge of regulations relating to clinical manufacturing, packaging and distribution activities (CGMP, GCP).
- APICS or CSCMP certification a plus.
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The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.
This description is not intended to be constructed as an exhaustive list of duties, responsibilities, or requirements for the position. This position may change or assume additional duties at any time. The employee may be requested to perform different or additional duties as assigned. All Employees are expected to adhere to all company policies and act as a role model for company values.
Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
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