Our commitment to people with muscle diseases
is our greatest strength
On World FSHD Day and every day, Dyne is dedicated to making a difference by advancing potentially life-transforming therapies for individuals and families living with FSHD.

Vivarium Manager

Department: 105 Research Ops

Location: Waltham, MA

Company Overview:

Dyne Therapeutics is building a leading muscle disease company dedicated to advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE™ platform, Dyne is developing modern oligonucleotide therapeutics that are designed to overcome limitations in delivery to muscle tissue seen with other approaches. Dyne’s broad portfolio of therapeutic candidates for serious muscle diseases includes programs for myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). For more information, please visit https://www.dyne-tx.com/, and follow us on TwitterLinkedIn and Facebook.

Role Summary:

The Vivarium Manager at Dyne will be an organized, detail and customer service-oriented member of our Research Operations team. This team member will provide an efficient and compliant Vivarium facility to support Dyne’s drug development programs. The successful candidate will be willing to collaborate, adapt, seek continuous operational optimization and be able to perform at a high level in a fast-paced environment. This is an excellent opportunity to develop a facility and associated programs contributing to delivering for our patients.

Primary Responsibilities Include:

  • Responsible for all vivarium related activities and staff to ensure outstanding resident care and a collaborative environment
  • Uphold and enforce standards of the Animal Welfare Act for all facility residents
  • Able to generate, implement, update and ensure compliance with all operational SOPs
  • Train all facility users on operational SOPs and monitor for compliance
  • Current and able to manage deployment of updates for national and state regulatory policies
  • Schedule, oversee and manage all studies; participate and assist with animal related procedures as needed
  • Work with our scientists and assist in study protocol generation
  • Generate, execute and participate in disease control and treatment programs; manage sentinel and water testing programs
  • Oversee the maintenance of the facility and maintain records associated with it including temperature, humidity, base building equipment related to the facility, equipment housed in the facility in conjunction with Research Operations, and animal health according to study protocols
  • As a leading member of our IACUC, proactively participate in the generation, review, and amendments of protocols; conduct post-approval monitoring
  • Collaborate with consulting Veterinarian on protocols and resident care as needed
  • Host and represent the company for all inspections with Veterinarian, IACUC and agencies
  • Primary contact for facility emergencies

 

Education and Skill Requirements:

  • Bachelor’s Degree with a concentration in Life Sciences required
  • 3-5 years of experience as a Vivarium manger/supervisor
  • LATG Certification required (ALAT advancing toward LATG may be considered).
  • Eligibility as holder of a DEA permit required
  • Proven track record of developing and implementing efficient and effective procedures and programs that create an exceptional vivarium
  • Experience of developing and leading high performing teams consisting of internal and external resources
  • Proficient with various routes of administration (i.p., i.v, p.o and s.c) and sample collection
  • Familiar with ABSL2 operating procedures
  • Effective oral and written communication skills
  • Proactive self-starter able to work independently and as part of multifunctional teams
  • Breeding and Colony Management Experience preferred
  • Familiarity with electronic Colony Management Systems preferred
  • The successful candidate will be self-motivated, able to make sound judgements and use discretion with confidential information
  • May need to stand or sit for extended periods of time
  • Must be able to lift 50 pounds

The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements.  Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.

This description is not intended to be constructed as an exhaustive list of duties, responsibilities, or requirements for the position. This position may change or assume additional duties at any time.  The employee may be requested to perform different or additional duties as assigned. All Employees are expected to adhere to all company policies and act as a role model for company values.

Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.


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