Our commitment to people with muscle diseases
is our greatest strength

Director, Global Medical Affairs Lead (DMD and FSHD)

Department: 122 Medical Affairs

Location: Waltham, MA

Company Overview:

Dyne Therapeutics is building a leading muscle disease company dedicated to advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE™ platform, Dyne is developing modern oligonucleotide therapeutics that are designed to overcome limitations in delivery to muscle tissue seen with other approaches. Dyne’s broad portfolio of therapeutic candidates for serious muscle diseases includes programs for myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). For more information, please visit https://www.dyne-tx.com/, and follow us on TwitterLinkedIn and Facebook.

Role Summary:

The Global Medical Affairs Lead (GMAL) will serve a critical role by supporting Dyne’s lead DMD and FSHD Programs. Internally, the GMAL will be accountable as the Global Medical Affairs representative on key cross-functional, and highly visible teams including Program Development Teams, Core DMD and FSHD Teams, and Clinical Development sub-teams, and eventually Brand Teams. In addition, the GMAL will be expected to master the scientific and medical literature/data associated with the FORCE platform, as well as the DMD and FSHD therapeutic areas, and lead/support efforts to enhance and communicate Dyne’s scientific leadership within these stated therapeutic areas. The incumbent will also play a key role in congress, symposia and publication strategy. Externally, the GMAL will develop the strategy around key opinion leader (KOL) engagement, advisory boards and expert committees.  The GMAL will also be closely partnered with his/her commercial counterparts to ensure a cohesive brand strategy and tactical plan, TPP development, KOL engagement plans, Payer engagement plans, etc. The role will also interface with Dyne’s partners in the development of partnered assets should that be required.

This role is based in Waltham, MA without the possibility of being a remote role. This role reports to the SVP, Global Head of Medical Affairs.

Primary Responsibilities Include:

  • Serve as a Medical subject matter expert on ASOs and other therapeutic modalities for DMD and FSHD
  • Serve as internal expert on medical literature / data associated with DMD and FSHD
  • Represent GMA on cross-functional teams supporting assets in the pipeline
  • Lead development and execution of global Medical plans in line with overall Corporate and Product strategies and priorities
  • Partner closely with commercial to develop and drive commercial plans and tactics, patient identification efforts, patient journey mapping
  • Lead/support congress, symposia and ad board strategy development and creation of content.
  • Develop KOL and Payer engagement strategy including mapping landscape, outreach plans, relationship management
  • Develop deep understanding of the diagnostic challenges for these therapeutic areas
  • Acts as role model of integrity and compliance

Education and Skills Requirements:

  • Doctorate degree (MD, PhD, PharmD) with a focus on rare diseases, neuromuscular experience (or related discipline) would be a plus; experience with ASOs also a plus
  • 3-5 years of relevant experience in rare diseases; neuromuscular or related field a plus
  • Analytical, with a track record of delivering against goals while working in high performing diverse teams
  • Demonstrated success in operating effectively in highly matrixed organizations where influencing skills are critical to day-to-day success
  • Ability to quickly adapt to new disease areas or therapeutic modalities
  • Experience in building strong and effective relationships with thought leaders, healthcare professionals, including laboratory professionals
  • Articulate with excellent communication and influencing skills
  • Willing to travel
  • Recognized by former peers, colleagues, managers and direct reports for attributes congruent with Dyne Values
  • Candidates must be authorized to work in the U.S.

The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements.  Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.

This description is not intended to be constructed as an exhaustive list of duties, responsibilities, or requirements for the position. This position may change or assume additional duties at any time.  The employee may be requested to perform different or additional duties as assigned. All Employees are expected to adhere to all company policies and act as a role model for company values.

Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

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