Our commitment to people with muscle diseases
is our greatest strength
On World FSHD Day and every day, Dyne is dedicated to making a difference by advancing potentially life-transforming therapies for individuals and families living with FSHD.

Associate Director, Program Management

Department: 140 Program Management

Location: Waltham, MA

Company Overview:

Dyne Therapeutics is building a leading muscle disease company dedicated to advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE™ platform, Dyne is developing modern oligonucleotide therapeutics that are designed to overcome limitations in delivery to muscle tissue seen with other approaches. Dyne’s broad portfolio of therapeutic candidates for serious muscle diseases includes programs for myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). For more information, please visit https://www.dyne-tx.com/, and follow us on TwitterLinkedIn and Facebook.

Role Summary:

Dyne is seeking an experienced operational leader for the Associate Director of Program Management role. This Program Manager (PM) will work closely with the program team lead to manage one of our drug development program teams as defined by the governance framework, executing the program strategy, and ensuring operational excellence. This person will play a key role in organizing and advancing critical R&D programs, facilitating timely and impactful decisions, and developing project, program, and portfolio strategy, milestones, and timelines. Additionally, this individual will have broad responsibilities to manage new early research projects and to support research needs in our rapidly growing organization.  This position is located in Waltham, MA and reports directly to VP, Head of Program and Alliance Management or his/her designee. 

The ideal candidate is a highly motivated individual with exceptional communication and collaboration skills. This position will afford the qualified candidate an opportunity to build and contribute to an innovative platform technology and advance Dyne's mission of pioneering life-transforming therapies for patients with serious muscle diseases.

Primary Responsibilities Include:

  • Partner with program team leaders to shape the program strategy, goals, and plans and ensure alignment with senior management and broader Dyne strategy
  • Provide strategic and operational support for Dyne research, drug discovery, and early development programs
  • Proactively contribute to operational project planning, risk anticipation / mitigation, team and meeting management, and coordination of decision-making. Create and maintain integrated activity plans with milestones/goals, key events, scenarios and other planning tools
  • Manage program team meetings, including leading discussions to drive to effective decision-making, agenda creation, and meeting minutes
  • Provide guidance to teams and line function members in negotiating challenges and driving to key decisions and milestones for programs
  • Contribute to strategy reviews for Dyne research portfolio
  • Partnering with Finance, support the annual goal and budget-setting process and track progress/resources throughout the year
  • Contribute to and/or lead diverse initiatives to improve Dyne’s R&D operations, planning, and execution, as needed

Education and Skills Requirements: 

  • Ph.D., or MS with 4+ years of industry experience, or BS with 6+ years of industry experience
  • Program management experience and familiarity with the drug development process from discovery to clinic
  • Comfortable operating in a fast-paced cross functional environment and exerting influence and negotiating without direct authority
  • Ability to constantly re-prioritize and adapt to a shifting discovery landscape – positive, persistent, flexible, and creative in the face of change
  • Demonstrated leadership experience
  • Excellent conflict-resolution and general people skills, ability to negotiate wide variety of personality types, highly collaborative
  • Proven track record of independence, with high level of integrity, accuracy, and attention to detail
  • Excellent communication skills (presentations, writing, slides, meeting facilitation)
  • Ability to facilitate successful cross functional communication and collaboration in the face of complex and time-sensitive challenges
  • Proficiency in Microsoft Office Suite, SharePoint, and working knowledge of project management software such as Smart Sheet, Microsoft Project, Office Timeline, One Pager, etc.
  • Previous experience with regulatory filings (INDs, CTAs, etc.) with various health authorities (FDA, EMA, etc.), alliance management experience, and familiarity with rare disease field a plus

The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements.  Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.

This description is not intended to be constructed as an exhaustive list of duties, responsibilities, or requirements for the position. This position may change or assume additional duties at any time.  The employee may be requested to perform different or additional duties as assigned. All Employees are expected to adhere to all company policies and act as a role model for company values.

Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.


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